Sensor utilizing Raman spectroscopy for non-invasive monitoring of analytes in biological fluid and method of use

摘要

A noninvasive Raman sensor and an associated method of measuring at least one parameter of a sample, such as the presence or concentration of an analyte. The sensor includesPP(a) at least one source of light capable of irradiating the sample with substantially monochromatic light;PP(b) a filtering module for filtering light scattered by the sample, that includes at least one bandpass filter capable of transmitting two different spectral windows; andPP(c) at least one detector.PP The method includesPP(a) irradiating a sample with light from a source of substantially monochromatic light,P P(b) collecting light that is scattered by the sample,PP(c) analyzing the scattered light by passing the light through a filtering module that includes at least one bandpass filter that is transmissive for at least two spectral windows, andPP(d) detecting light that has been filtered by said filtering module.PP The sample may be a biological fluid or other substance that has been obtained from the body or it may be a biological fluid or other substance located within a body part.