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Sphingoglycolipids as markers for multidrug resistant cancers
Sphingoglycolipids as markers for multidrug resistant cancers
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机译:鞘脂糖脂作为多药耐药性癌症的标志物
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摘要
The present invention involves the identification of sphingoglycolipid species that are indicative of multidrug resistance in certain types of cells, including cancer cells. The association of multidrug resistance with the expression of certain sphingoglycolipids provides a new method for identifying multidrug resistant cancers. In addition, it has been determined that reducing the levels of certain sphingoglycolipids results in enhanced chemosensitivity of drug resistant cancer cells. This offers the opportunity to develop new treatments for multidrug resistant cancers.
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