Compounds inhibiting the association of the PDGF receptor and phosphatidylinositol 3-kinase and their use

摘要

The present invention provides compounds that inhibit the association of platelet-derived growth factor and phosphatidylinositol 3- kinase. The present invention also provides pharmaceutical compositions that contain a compound that inhibits the association of platelet- derived growth factor and phosphatidylinosital 3-kinase, and methods of treating cancer, restenosis, arthritis, dermatitis, atherosclerosis, vein graft intimal hyperplasia, neointimal hyperplasia of vascular smooth muscle and psoriasis using compounds that inhibit the association of platelet- derived growth factor and phosphatidylinositol 3-kinase.