Method for suppressing harmful side effects due to administration of GnRH or GnRH agonist

摘要

The use of a compound of formula I CHEM wherein R1 and R3 are, independently, -H, -CH3, -CO(C1-C6 alkyl), or -COAr, where Ar is optionally substituted phenyl; R3 is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a pharmaceutical formulation for inhibiting detrimental side-effects of GnRH or a GnRH agonist in a mammal.