(S) N and N ' - bis 2 hydroxy 1 (hydroxymethyl) ethyl the 5 (2 hydroxy 1 oxo propyl) amino 2,4,6 triiodo 1,3 benzenjikarubokishiamido (C5 of direct condition or branching condition - C6) alcohol or the manner which makes crystallize from those blends

摘要

Disclosed is a new process for the crystallization of (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide (I), using a linear or branched (C5-C6) alcohol or their mixtures.