Novel optically active. Beta. - hydroxy -. Alpha. - bromo -. Alpha. - fluorocarbonates, which are considered to be useful intermediates of the bioactive compounds, and the synthesis of the optically active substance with high asymmetric yield and the combination of the optically active substances A novel, 2-bromo-2-fluoroketene silyl acetal, which is useful as an intermediate intermediate, and its synthesis method. A novel 2-bromo-2-fluoroketene silyl acetal was obtained by the reaction of a dibromofluoroacetate and a silyl halide compound, and the catalyst was catalyzed by this 2-bromo-2-fluoroketene silyl acetal and aldehyde It is possible to catalyze asymmetric synthesis of a new optically active. Beta. - hydroxy -. Alpha. - bromo -. Alpha. - fluorocarbon ester by reacting in the presence of the amount of chiral Ruiz acid.
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