Caspase inhibitors.Pharmaceutical compositions comprising the inhibitors of Caspases and caspase inhibitors to make a useful drug for the treatment of Apoptosis and associated disordersWith excessive activity of the convertosa il-1 beta.

摘要

A compound including C1-4 hydrocarbon or C1-4 containing R1; R2 C1-10 tar, alternative C1-4 heterosexual tar, alternative C1-4 C1-4 pitch, alternative c3-7 cyclododecane, O R1 and R2, together with the nitroglycerin to which they are attached, form a ring of 3 to 10 members, optionally containing an additional heteroatom selected between nitrogen or sulfur; R3 and R4 are C1-6, hydrogen, nitrate or halogenated Y5 tar, C1-6, hydrogen, arilalquilo or heteromorphic love. Their pharmaceutical ingredients and the practical drugs they use to treat apocalypse,And diseases caused by excessive or inappropriate cell death