Use of a combination of an anti estrogen Plus progestin for the preparation of a Medicament useful for providing contraception and a Kit deanticonceptivos adapted for oral administration DayRia

摘要

An effective contraceptive drug is prepared by using a mixture of antiestrogen and progestin, which includes an effective contraceptive with a mixture of formula hormone (I) or (II), wherein R1 is h, O H, carboacoxi c2-12, alcoxi C1-12, halogen genome or poli fluorinated alcoxi C1-12; R2 is h, oh, Carbooxy c2-12, ALCOXY C1-12, halogenated monkey - or polyfluoropropoxyc1-12, cyanogen, C1-6 tar or trifluoromethyl, provided that R1 is h, R2 is not Oh; R3 and R4 are h, oh, carbooxy c2-12, alcox C1-12, halogenated monkey - or polyfluoropropoxyc1-12 or cyanogen, provided that R1 is not C12; Oh is C16.Cyanogen, nitric acid, trifluoromethyl or halide; n is 2 or 3; it is a 5-7 member, saturated, partially saturated or unsaturated mixed cycle containing a nitro group, which may contain a second heteroatom, from - O -.- en...C1-6, N=,2.1.2.2.1.2 and S (o) m; m is 0-2; or 0-2; or 0-2; or 0-2, according to 28 days of menstruation, a 28 day proggina. In addition, a set of contraceptives suitable for daily oral use was introduced.