Fenilaminoalquilcarboxilico acid derivatives useful as stimulants of the beta3 adrenoceptors, Pharmaceutical composition, beta3 adrenoceptor stimulant,Uses in the manufacture of medicinal products and Manufacturing process

摘要

Benzoic acid derivatives represented by general formula (I)(R1 represents a hydrogen Xi group, a lower alcox group, an amino group, an alicic amino group or a monomer or di - (low tar) amine group, which may have one hydrogen Xi group or more ALCOXY groups as substitutes; R2 represents a hydrogen Xi group or a lower tar group; R3 represents a hydrogen gene atom) Or a halogenated atom; R4 and R5 are equal or different, each representing a hydrogen atom, a halogenated atom or a lower tar group; a represents a lower tar group; C atom with (R) mark represents a C constituent type atom.The C atom labeled with (s) is a C atom, which is a drug acceptable C atom, has excellent induction effect, can stimulate amphetamine 3-adrenergic, and is an effective medium to prevent obesity, hyperglycemia and intestinal ADHD and other diseases, Polar, incontinence,The depreciation of diseases caused by cholesteric hyperactivity disorder. Drugs and stimulants including these derivatives A man who cures disease 2. Use of derivatives in drug manufacturing The process of making a pharmacist, including the pharmaceutical component of the derivative or acceptable table salt as an essential part of it.