首页> 外国专利> 12,13- (pyranosyl) -indolo 2,3-alpha pyrrolo 3,4-c carbazole compounds and 12,13- (pyranosyl) -puro 3,4-c indole 2,3-alpha carbazole, a process for its preparation and pharmaceutical compositions containing the same

12,13- (pyranosyl) -indolo 2,3-alpha pyrrolo 3,4-c carbazole compounds and 12,13- (pyranosyl) -puro 3,4-c indole 2,3-alpha carbazole, a process for its preparation and pharmaceutical compositions containing the same

机译:12,13-(吡喃基)-吲哚[2,3-α]吡咯并[3,4-c]咔唑化合物和12,13-(吡喃基)-puro [3,4-c]吲哚[2,3-α]咔唑,其制备方法和含有该咔唑的药物组合物

摘要

Invention Patent: B "COMPOUNDS 12,13- (PYRANOSYL) -INDOLO [2,3-ALFA] PIRROLEY [3,4-C] CARBAZOL E 12,13- (PYRANOSYL) -HOLE [3,4-C ] INDOLO [2,3-ALFA] CARBAZOL, A PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME "D. Compounds of formula (I): where: R ~ 1 ~ and R ~ 2 ~, which can be identical or different, represent a group of UV formula where U represents a single bond or an alkylene chain that is optionally substituted and / or unsaturated and V is as defined in the description, G represents an oxygen atom or an NR ~ 3 ~ group where R ~ 3 ~ is as defined in the description, X represents a hydrogen atom, a hydroxy, alkoxy, mercapto or alkylthio group , Y represents a hydrogen atom, or X + Y represents a carbonyl group, X ~ 1 ~ represents a hydrogen atom, a hydroxy, alkoxy, mercapto or alkyl thio group, Y ~ 1 ~ represents a hydrogen atom, or X ~ 1 ~ + Y ~ 1 ~ represents a carbonyl group, R ~ 4 ~, R ~ 5 ~ and R ~ 6 ~ are as defined in the description, their isomers, and their addition salts with a pharmaceutically acceptable acid or base.
机译:发明专利:“化合物12,13-(吡喃基)-吲哚[2,3-ALFA]吡咯[3,4-C]咔唑E 12,13-(吡喃基)-孔[3,4-C] INDOLO [2,3-ALFA]咔唑,其制备方法和含有相同“ ”​​的药物成分。式(I)的化合物:其中:R〜1〜和R〜2〜可以相同或不同,表示一组UV式,其中U表示可被取代和/或不饱和的单键或亚烷基链式中,V代表说明书中的定义,G代表氧原子或NR 3〜基团,R 3代表说明书中的定义,X代表氢原子,羟基,烷氧基,巯基或烷硫基,Y代表氢原子,或X + Y代表羰基,X〜1〜代表氢原子,羟基,烷氧基,巯基或烷硫基,Y〜1〜代表氢原子,或X〜1〜+ Y 〜1〜代表羰基,R〜4〜,R〜5〜和R〜6〜如说明书中所定义,它们的异构体以及它们与药学上可接受的酸或碱的加成盐。

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