Extended release preparation, process for producing an extended release preparation, and pharmaceutical composition

摘要

"PREPARATION OF PROLONGED RELEASE, PROCESS FOR THE PRODUCTION OF A PROLONGED RELEASE PREPARATION, AND PHARMACEUTICAL COMPOSITION". The present invention is to provide a prolonged release preparation that comprises a compound having antagonistic activity of angiotensin II, its prodrug or its salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and has antagonistic activity of angiotensin II with the maintenance of the circadian rhythm of blood pressure for a long period.