Method for preparing Cycle (ASP dfen - nmeval - Arg - Gly); compounds pentapu00c9ptidos linear Intermediates in the synthesis of the compound Cycle (ASP dfen nmeval - Arg - Gly -

摘要

A process for preparing cyclic pantapeptido cyclic (Arg - Gli - ASP - dfen - nmeval)For the cyclization of a linear Pentapeptide chosen from the group consisting of H - Arg (PBF) - Gly - ASP (obz) - nmeval dfen - - Oh, H - Gly - ASP (obzl) - dfen - nmeval - Arg (PBF) - Oh.H - ASP (obz1) - dfen - nmeval - Arg (PBF) - gli Oh, escicion subsequent Protective Group and, if appropriate,Further Transformation in its Salt acceptable from the Physiological Point of view.