3.4 - ciclobutendiona amino substituted Derivatives, Pharmaceutical composition, Preparation Method, inhibidoresde phosphodiesterase 5Useful in the treatment of benign hypertrophy of the Prostate, bladder incontinence, obstructed labor, dysmenorrhea, or Premature Ejaculation, erectile Dysfunctions and sexual.

摘要

The compounds corresponding to the General formula (i) in which R1 and R2 independently represent a hydrogen Atom, an alkyl group of 1 to 6 carbon Atoms.Alquilenio 2 to 6 carbon Atoms - (CH2) n - 6 cycloalkyl R3 represents a hydrogen Atom, a Group dalquilo of 1 to 6 carbon Atoms.W represents a Group for which nr4r5 R4 and R5 independently represent a hydrogen Atom, an alkyl group of 1 to 6 carbon Atoms.Alquelino 2 to 6 carbon ATOMS, alquinilo 2 to 6 carbon ATOMS, - (CH2) - 6 pp. ISBN cycloalkyl, c1-4 alkoxy - c1-4 alkyl, fluoroalquilo of 1 to 6 carbon Atoms.Perfluoroalkyl 1 to 2 carbon ATOMS, - (CH2) M - piridiloo group or R4 and R5 together form a Chain dalquileno 3 to 7 carbon Atoms or represent a Group.Pharmaceutical composition that comprises the preparation procedures, useful as inhibitors of phosphodiesterase.