首页> 外国专利> Compounds derived from pirido 2 ', 3': 5,6 pyrano 2,3-d azepine,Preparation Method, Pharmaceutical composition containing Said compound and use of the compound in the Treatment or prevention of disorders nicotinicEspecially the central nervous system or the gastrointestinal System.

Compounds derived from pirido 2 ', 3': 5,6 pyrano 2,3-d azepine,Preparation Method, Pharmaceutical composition containing Said compound and use of the compound in the Treatment or prevention of disorders nicotinicEspecially the central nervous system or the gastrointestinal System.

机译:源自吡里多[2',3':5,6]吡喃并[2,3-d]氮杂的化合物,制备方法,包含所述化合物的药物组合物以及该化合物在治疗或预防烟碱样疾病中的用途特别是中枢神经系统或胃肠系统。

摘要

Compounds of the General formula wherein R1 represents a hydrogen Atom, an alkyl group, fenilalquilo, fenilhidroxialquilo, furanialquilo or furanilhidroxialquilo, R2.Represents either a hydrogen Atom or a Halogen or a trifluoromethyl Group, cyano Hydroxy alkyl, alkoxy, Nitro, acetylAmino nr4r5 General formula wherein R4 and R5 each represent a hydrogen Atom or a Group dalquilo or Form, with the nitrogen Atom containing,A cycle in c4-c7 either a phenyl or naphthyl Group eventually substituted by a Halogen Atom or group trifluoromethoxy cyano, trifluoromethyl, Hydroxy alkyl, Nitro, acetyl,Methylenedioxy or alkoxy, and R3 represents a hydrogen Atom or a Halogen or alkyl group.
机译:通式化合物其中R1代表氢原子,烷基,fenilalquilo,fenilhidroxialquilo,呋喃萘基或呋喃基苯并基,R2代表氢原子或卤素或三氟甲基,氰基羟基烷基,烷氧基,硝基,乙酰基氨基nr4r式中R 4和R 5各自代表氢原子或达基基或形式,其中氮原子含有在c4-c7中的一个环,苯基或萘基最终被卤素原子或三氟甲氧基氰基,三氟甲基,羟基烷基取代,硝基,乙酰基,亚甲基二氧基或烷氧基,且R 3表示氢原子或卤素或烷基。

著录项

  • 公开/公告号CL2000000487A1

    专利类型

  • 公开/公告日2000-11-23

    原文格式PDF

  • 申请/专利权人 SANOFI-AVENTIS;

    申请/专利号CL2000000487

  • 申请日2000-03-03

  • 分类号A61K31/44;A61P25/00;C07D209/00;C07D221/00;C07D311/00;C07D491/22;

  • 国家 CL

  • 入库时间 2022-08-22 01:25:52

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