Pyrazine derivatives substituted Compounds, Pharmaceutical Composition and its use for treating or Preventing a disease related to serotonin, such as eating disorders,Especially obesity, Memory Disorders, Schizophrenia and mood disorders, among others.

摘要

The Invention relates to compounds of the General formula where a is aryl or heteroaryl is optionally substituted; (i) - CL -, - O -, - S -,- SO2 -, (ii) a nitrogen Atom substituted with c1-4 alkyl, aryl or C1 - 6, or (iii) a Chain of C1 - 8 alquileno chain or a heteroaryl with 2 to 8 Atoms in the chain.Optionally contains at least one unsaturation, and which can be replaced and / or be United through a Union Bridge,To form a partially or completely unsaturated saturated Ring with 3 to 8 members in the ring.