首页> 外国专利> Selection method of an oligonucleotide that specifically binds to a protein called 'White, oligocuerpo', which comprises Incubating the Protein with a Target oligonucleotide Library.Separate the molecules are not linked and amplify the Linked, and determining its specificity in a mixture of White.

Selection method of an oligonucleotide that specifically binds to a protein called 'White, oligocuerpo', which comprises Incubating the Protein with a Target oligonucleotide Library.Separate the molecules are not linked and amplify the Linked, and determining its specificity in a mixture of White.

机译:特异性结合称为“ White,oligocuerpo”的蛋白质的寡核苷酸的选择方法,该方法包括将蛋白质与靶寡核苷酸文库一起孵育。分离未连接的分子并扩增所连接的分子,并在以下混合物中确定其特异性白色。

摘要

Using a Library of oligonucleotide fragments and Synthetic peptides corresponding to different Proteins.Together with a strategy that we call White replacement, we have successfully produced equivalent reactive Antibodies in their ability to recognize the target Proteins.In both the native and denatured form, and are useful for similar applications which are used for the monoclonal or polyclonal Antibodies.We called oligocuerpos to these Reagents.
机译:使用对应于不同蛋白质的寡核苷酸片段和合成肽库,结合我们称为白色替代的策略,我们已经成功地产生了等效的反应性抗体,能够识别目标蛋白质,无论是天然形式还是变性形式,并且可用于单克隆或多克隆抗体的类似应用。我们将寡核苷酸称为这些试剂。

著录项

  • 公开/公告号CL2000002203A1

    专利类型

  • 公开/公告日2001-10-05

    原文格式PDF

  • 申请/专利权人 SANTA COLOMA TOMAS ANTONIO;

    申请/专利号CL2000002203

  • 发明设计人 SANTA COLOMA TOMAS ANTONIO;

    申请日2000-08-17

  • 分类号C12Q1/68;

  • 国家 CL

  • 入库时间 2022-08-22 01:25:52

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