New formulations of controlled release oral dosage and with - containing monohydrochloride R - (Z) - (metoxii (Mino) - 1-azabicyclo 2,2,2 - 3 - Sep II) acetonitrile

摘要

1. An oral dose and controlled release form of acetone (compound x) containing [R - (z)] a - (methoxy) a - (1-azabicyclo [2.2.2] oct-3-il): composition mg / plate% X 0005-0, 1b. L.P. ethyl cellulose 22, 5-37, 15-25dihydroxylate 63, 3, 42, 2-52, 2 microcrystalline calcium dicarboxylic acid 30.0-40.0 19.8-26 7. Compressed with sheet, with 3% weight gain and sealant solution, it is composed of aqueous solution of hydroxycellulose containing plasticizer in purified water, with solid concentration of 10%, followed by aqueous dispersion layer of cellulose containing oleic acid.Ammonium hydroxide and plasticizer, or a water dispersion mixture of ethylene with ammonium hydroxide oleic acid and a water dispersion and plasticizer of hydroxypropylmethylcellulose.