首页> 外国专利> Process for preparing allogeneic cells population, population of T-cells and use thereof for inhibiting graft reaction versus host

Process for preparing allogeneic cells population, population of T-cells and use thereof for inhibiting graft reaction versus host

机译:制备同种异体细胞群体的方法,T细胞群体及其在抑制移植物抗宿主反应中的用途

摘要

Mammalian subject is the graft versus host disease(GVH disease) treating bone marrow derived disease and generating in the cellular transplantation therapy that carries out,It can be prevented and be mitigated by least transplanting homogeneous variant cell and the T- cells in ingredient give oxidative stress in vitro with dosage appropriate,Such as pass through T- cell suspensions with the mixing bubble of ozone and oxygen. The method be also included within using while oxidative stress with ultraviolet light cell. Oxidative stress causes the intracellular inflammatory factors of T- to generate reduction and breeder reaction reduction.
机译:哺乳动物受试者是治疗骨髓源性疾病并在细胞移植治疗中产生的移植物抗宿主病(GVH病),可通过最少移植同质变异细胞和成分中的T细胞氧化来预防和减轻适当的剂量在体外产生应力,例如通过T细胞悬浮液,并注入臭氧和氧气的混合气泡。该方法也包括在与紫外线电池同时氧化应激的使用范围内。氧化应激导致T-的细胞内炎性因子减少,而种系反应减少。

著录项

  • 公开/公告号CZ20010316A3

    专利类型

  • 公开/公告日2001-10-17

    原文格式PDF

  • 申请/专利权人 VASOGEN IRELAND LIMITED;

    申请/专利号CZ20010000316

  • 发明设计人 SPANER DAVID ELLIOTT;

    申请日1999-07-30

  • 分类号C12N5/08;A61K35/14;A61K35/28;A61P37/06;

  • 国家 CZ

  • 入库时间 2022-08-22 01:25:46

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