首页> 外国专利> OPTICAL ACTIVE 1-(4-NITROPHENYL)-4-METHYL-7,8-METHYLEN DIOXI-3,4-DIHYDRO-5H-2,3-BENZODIAZEPINE AND PROCESS FOR PRODUCING IT

OPTICAL ACTIVE 1-(4-NITROPHENYL)-4-METHYL-7,8-METHYLEN DIOXI-3,4-DIHYDRO-5H-2,3-BENZODIAZEPINE AND PROCESS FOR PRODUCING IT

机译:光学活性的1-(4-硝基苯基)-4-甲基-7,8-甲基二氧-3-3,4-二氢-5H-2,3-苯并二氮杂AND及其生产方法

摘要

the object of the invention is formula (i) 1 - (4 - nitro phenyl) - 4 - methyl - 7,8 - methylene - dioxi - 3,4 - dihydro - 5h - 2,3 - and benzodiazepine enantiomerjei ezekelu0151u00e1llu00edtu00e1su00e1ra procedure, which consists inin the formula (ii) 1 - (4 - nitro phenyl) - 4 - methyl - 7,8 - methylene - dioxi - 5h - 2,3 - benzodiazepines (iii) u00e1ltalu00e1nosku00e9pletu0171, r - or s - 2 - amino - 1 configuration.alkan - diphenyl - 1 - 1 - ol - szu00e1rmazu00e9kbu00f3l, where r1 and r2 are different, and jelentu00e9sehidrogu00e9natom having carbon numbers in the range of 1 to 4, a straight or branched lu00e1ncu00faalkilcsoport,furthermore, helyettesu00edtetlen phenyl - or benzilcsoport, u00e9s1 mu00f3lekvivalens boru00e1nbu00f3l or a boru00e1nkomplexbu0151l ku00e9pzettaddukttal is reduced.according to the invention is produced by the compound of formula (i) in a vegyu00fcletekszintu00e9zise enantiomerjei medicinal intermediates.
机译:本发明的目的是式(i)1-(4-硝基苯基)-4-甲基-7,8-亚甲基-二恶英-3,4-二氢-5h-2,3-和苯并二氮杂对映体ezekel u0151 u00e1ll u00edt u00e1s u00e1ra程序,该程序包含在式(ii)1-(4-硝基苯基)-4-甲基-7,8-亚甲基-二恶英-5h-2,3-苯并二氮杂(iii) u00e1nosk u00e9plet u0171,r-或s-2-氨基-1构型。烷烃-二苯基-1-1-ol-sz u00e1rmaz u00e9kb u00f3l,其中r1和r2不同,并且jelent u00e9sehidrog u00e9n碳数在1-4范围内的是直链或支链l u00e1nc u00faalkilcsoport,此外,helyettes u00edtetlen苯基-或benzilcsoport, u00e9s1 m u00f3lekvivalens bor u00e1nb u00f3l或a bor 根据本发明,由式(i)的化合物在纯的对映异构体医学中间体中通过式(i)的化合物产生。

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