Process for the preparation of 4, 10beta-diacetoxy-2alpha -benzoyloxy-5beta,20-epoxy-1-hydroxy-9-oxo-19-norcyclopropa(G)tax-11-en-13alpha-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate

摘要

A 4,10 beta -diacetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate, and the preparation thereof by crystallisation from a water-alcohol or water-ketone solution, are disclosed.