首页> 外国专利> Nye heterocykloalkylbenzocyklobutan- og heteroarylbenzocyklobutanforbindelser, fremgangsmåte ved deresfremstilling og farmasöytiske sammensetninger inneholdende dem

Nye heterocykloalkylbenzocyklobutan- og heteroarylbenzocyklobutanforbindelser, fremgangsmåte ved deresfremstilling og farmasöytiske sammensetninger inneholdende dem

机译:新型杂环烷基苯并环丁烷和杂芳基苯并环丁烷化合物,其制备方法和含有它们的药物组合物

摘要

Compounds of formula (i): (see appended drawing in bopi) in which: (see appended drawing in bopi) represents a single bond or a double bond, n is an integer between 1 and 6 inclusive, r1, r2 represents a group chosen from among hydrogen atom, alkyl group (c1 - c6), linear or branched, aryl or arylalkyl radical, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, a heterocycloalkyl, heterocycloalkylalkyl, heteroaryl radical, and heteroarylalkyl, x represents a group chosen from oxygen atom, a group s (o) m in which m is an integer between 0 and 2 are included, and nr3 wherein r3 represents a group such as defined in the description, t represents a cycloalkyl group (c3 - c10) monocyclic or polycyclic, possibly containing within the system of the cyclic an oxygen atom, an atom of selenium, a group of formula s (o) p, nr3, or sir4 r5 in which p, r3, r4 and r5 are as defined in the description, their isomers, as well as their addition salts with a pharmaceutically acceptable acid or base. Medicinal products.
机译:式(i)的化合物:(参见bopi的附图)其中:(参见bopi的附图)表示单键或双键,n为1至6之间的整数,包括r1,r2表示所选的基团在氢原子,烷基(c1-c6),直链或支链,芳基或芳基烷基,环烷基,环烷基烷基,烯基,炔基,杂环烷基,杂环烷基烷基,杂芳基和杂芳基烷基中,x表示选自氧原子的基团,包括其中m是0和2之间的整数的基团s(o)m,和nr3,其中r3代表如说明书中所定义的基团,t代表单环或多环的环烷基(c3-c10),可能包含在环状体系中,一个氧原子,一个硒原子,一组式s(o)p,nr3或sir4 r5,其中p,r3,r4和r5如说明书中所定义,其异构体为以及它们与可药用酸或碱的加成盐。药品。

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