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New polymorphs dihydrochloride lesopitron and hydrated forms, methods of preparation and compositions containing them.
New polymorphs dihydrochloride lesopitron and hydrated forms, methods of preparation and compositions containing them.
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机译:新的多晶型二盐酸来苏必通和水合形式,制备方法和含有它们的组合物。
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摘要
It comprises the new polymorphs I and II of Lesopitron dihydrochloride, characterized by their infrared spectra and their X-ray diffraction patterns. They are obtained by crystallization of Lesopitron dihydrochloride. It also comprises the forms I-hydrate and II-hydrate, which are obtained from the corresponding polymorphs, which have a water content from 3 to 6% and from 1.5 to 2.5%, respectively. These products are used in human medicine mainly due to their pharmacological activity over the central nervous system.
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