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Non Peptide compounds as growth hormone secretagogues

机译:非肽化合物作为生长激素促分泌剂

摘要

Refers to a non Peptide Compound of formula I wherein R1 is c6h5ch2och2 C6H5 -, (CH2) 3 - indole - 3 - ilmetilo; and is pirrolidinilo, 4 - metilpiperidinilo, nr2r2 is C1 - C6 alkyl; R2, R3 is 2 - naphthyl,PHENYL substituted W; W is H, F, CF3, c1-c6 alkoxy, phenyl; R4 is H, CH3. Also refers to a formulation also contains an agent such as Bone antireabsorcion bisphosphonate.Non Peptide compounds have activity as growth hormone secretagogues can therefore be useful for the treatment of growth hormone deficiency in cowsSheep, Poultry
机译:指式I的非肽化合物,其中R 1为c 6h 5ch 2 och 2 C 6 H 5-,(CH 2)3-吲哚-3-ilmetilo;并且是吡咯烷基,4-甲哌啶基,nr2r2是C1-C6烷基; R2,R3为2-萘基,苯酚取代的W; W是H,F,CF 3,C 1 -C 6烷氧基,苯基; R4是H,CH3。也指制剂中还包含诸如抗骨吸收剂双膦酸盐之类的成分。非肽类化合物具有生长激素促分泌剂的活性,因此可用于治疗牛的生长激素缺乏症

著录项

  • 公开/公告号PE14682000A1

    专利类型

  • 公开/公告日2000-12-20

    原文格式PDF

  • 申请/专利权人 ELI LILLY AND COMPANY;

    申请/专利号PE20000000127

  • 申请日2000-02-18

  • 分类号C07K5/062;A61K38/05;

  • 国家 PE

  • 入库时间 2022-08-22 01:24:16

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