首页> 外国专利> Mannich base, India, its preparation procedures, drugs containing these compounds and their use in drug preparation

Mannich base, India, its preparation procedures, drugs containing these compounds and their use in drug preparation

机译:印度曼尼希基地,其制备程序,含有这些化合物的药物及其在药物制备中的用途

摘要

It refers to the Indian Manichean base replacing formula I, where R1 is h, C1-C10 asphalt, arilo, heterosexual; R2 is h, F, Cl, Br, CF3, CN, no2nhr8, SR9, or10, CO (or11),R3 is, inter Alia, CH (R13) n (R14) (R15);2) C12 (joint formation) C6 (or C12) C2 (or C12 (joint formation) C2) C6 (or C12 (joint formation) C2 (or C12) C2 (or (2) R16 is C1-C10 tar, arilo, Except for the following compounds: R3 is ch (R13) n (R14 (R15) or r4-r7 is h; R13 is phenyl; R14 and R15 are CH2) 5; R1 is h, CH3, benzene, etc.; these compounds are the preferred compound 3 - (dimethylamine) - 1h-indol-2-carboxilato de ethyl; [(5-fluoro-1h-indol-3-il) - phenylmethylphenylpropyl] - dimethylamine,There are others He also mentioned a preparatory process Compound I may help control pain, inflammation, allergic reactions, drug abuse, alcohol, diarrhea, gastritis, ulcer, allergic reactions, glaucoma, asthma
机译:它指代印度马尼基基地取代式I,其中R1为h,C1-C10沥青,arilo,异性恋; R2为h,F,Cl,Br,CF3,CN,no2nhr8,SR9或10,CO(or11),R3为Alia,CH(R13)n(R14)(R15); 2)C12(接头形成) C6(或C12)C2(或C12(接头形成)C2)C6(或C12(接头形成)C2(或C12)C2(或(2)R16是C1-C10焦油,arilo,以下化合物除外:R3是ch(R13)n(R14(R15)或r4-r7是h; R13是苯基; R14和R15是CH2)5; R1是h,CH3,苯等;这些化合物是优选的化合物3-(二甲胺)-1h-吲哚-2-羧甲基去乙基; [(5-氟-1h-吲哚-3-il)-苯基甲基苯基丙基]-二甲胺,还有其他他还提到了制备过程化合物I可能有助于控制疼痛,炎症,过敏反应,药物滥用,酒精,腹泻,胃炎,溃疡,过敏反应,青光眼,哮喘

著录项

  • 公开/公告号PE20010993A1

    专利类型

  • 公开/公告日2001-10-06

    原文格式PDF

  • 申请/专利权人 GRUNENTHAL GMBH;

    申请/专利号PE20000001397

  • 发明设计人 GERLACH MATTHIAS;MAUL CORINNA;

    申请日2000-12-26

  • 分类号C07D209/14;C07D209/20;C07D209/32;C07D209/42;C07D403/02;C07D401/02;C07D405/02;C07D409/02;A61K31/404;

  • 国家 PE

  • 入库时间 2022-08-22 01:24:14

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