PHARMACUTIC COMPOSITION BASED ON FLAVOPEREIRIN AND ITS USE IN TREATMENT AGAINST HIV VIRUS

摘要

PCT No. PCT/FR93/00761 Sec. 371 Date Feb. 22, 1994 Sec. 102(e) Date Feb. 22, 1994 PCT Filed Jul. 26, 1993 PCT Pub. No. WO94/02146 PCT Pub. Date Feb. 3, 1994.Flavopereirine taken alone may act as an effective active agent in the struggle against HIV viruses in mammals, including humans. More specifically, it has been found that flavopereirine is an active agent which on its own, whether in vitro or in vivo exerts a selective inhibitlye action on viral HIV infection, particularly in patients infected by HIV-1. Thus, there is provided a method for the treatment of human immunodeficiency virus comprising administering to a human patient infected with human immunodeficiency virus an effective antiviral amount of a composition consisting of flavopereirine or a pharmaceutically acceptable salt or derivative thereof and a pharmaceutically acceptable carrier. The flavopereirine, or one of its salts or other acceptable pharmaceutical derivatives, is preferably administered in solid form containing approximately 250-500 mg of flavopereirine per dose.