NOVEL PROCESS FOR PREPARING N-ACETYL-(L)-4-CYANOPHENYLALANINE AC-(L)-PHE(4-CN)-OH AND N-ACETYL-(L)-P-AMIDINOPHENYLALANINE- -CYCLOHEXYLGLYCINE-'BETA'-(3-N-METHYLPYRIDINIUM)-ALANINE AC-(L)-PAPH-CHG-PALME(3)-NH2

摘要

Preparation of N-acetyl- (L) -4-cyanophenylalanine, Ac- (L) -Phe (4- -CN) -OH, compound of formula (IA), is performed by cleavage of the racemic compound, ethyl ester of N-acetyl- (D, L) -4-cyanophenylalanine, and a process for preparing a stereoisomer, Ac- (L) -pAph-Chg-PalMe (3) -NH 2, a compound of formula (II), using said intermediate, N-acetyl- (L) ) -4-kyanofenylalanínu.ŕ