BENZO-CONDENSED COMPOUNDS OF ACEPINONE AND PIPERIDINONE, USEFUL AS ACE AND NEP INHIBITORS.

摘要

COMPOUNDS THAT HAVE THE FOLLOWING FORMULA I, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, INCLUDING DOUBLE ACE AND NEP INHIBITORS AND SELECTIVE ACE INHIBITORS: WHERE: Y {SUP, 1} EY {SUP, 2} IS EACH ONE , ARYL, HALOGEN, OR ALCOXY; X IS O O S (O) {SUB, T}; A ES: T ES 0.1, O 2; MYN ARE INDEPENDENTLY 0 OR 1, AND WHERE R, R {SUP, 5}, R {SUP, 5A}, R {SUP, 5B}, R {SUP, 6}, R {SUP, 7}, R {SUP , 11}, QYR ARE DEFINED HERE.