pharmaceutical compositions derived from microemulsion-based gels, method for their preparation and new gels based on microemulsions.

摘要

The invention relates to a composition PHARMACEUTICAL INCLUDING ONE MADE microemulsion a hydrophilic component, a lipophilic component, a surfactant and a drug, so that the hydrophilic component, the lipophilic component and surfactant form, when EXAMINE ON A SCALE macroscopic, a solution of a phase. The hydrophilic component is dispersed as droplets COLLOIDAL in the lipophilic component or lipophilic COMPONENT COLLOIDAL as droplets dispersed IN hydrophilic component. In another alternative Hydrophilic Lipophilic COMPONENTS AND FORMING A microemulsion with bicontinuous structure so SUCH COMPONENTS ADJACENT CHANNELS ARE EXTENDED. The drug is dissolved in the component dispersed OR, IN THE CASE OF AN bicontinuous microemulsion structure, hydrophilic or lipophilic COMPONENT. The microemulsion is stabilized by the surfactant. Characteristically ADD A gelling AND WATER EMULSION TO GIVING WELL TO THIS FORM OF GEL.