The present invention is directed to a process forconducting optical resolution of a racemic mixture of an amino acidderivatives and a process for preparing an optically active amino acid usinga catalytic antibody enantioselectively hydrolyzing an amino acid esterderivative. The catalytic antibody and hybridoma producing said antibodyare also provided. The hybridomas in the present invention are typicallyproduced by stimulation with an antigen comprising as a hapten acompound of the formula:(see formula 3)wherein CBZ is N-benzyloxycarbonyl.
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