A PCAM-1 MARKER PROTEIN, NUCLEIC ACID SEQUENCES ENCODING PCAM-1 AND IMMUNOASSAYS FOR DETECTION OF PCAM-1

摘要

The present invention provides a cancer marker protein, PCAM-1, andpolynucleotides which identify and encode this protein. Detection of thismarker is useful in diagnosing and prognosticating cancer in a patient. Alsoprovided are expression vectors and host cells for expression of PCAM-1 aswell as antibodies raised against the PCAM-1 protein. In addition, a MonteCarlo like screening assay for identification of specific 8 mer sequenceswhich selectively bind proteins in a crude extract of tissues, cells or otherbiological fluids is provided.