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One-pot synthesis of alkyl 3-cyclopropylamino-2-(2,4-dibromo-3-(difluoromethoxy)benzoyl)-2-propenoate as a useful intermediate for antibacterial quinolone medicaments
One-pot synthesis of alkyl 3-cyclopropylamino-2-(2,4-dibromo-3-(difluoromethoxy)benzoyl)-2-propenoate as a useful intermediate for antibacterial quinolone medicaments
The present invention relates to a new and industrially advantageous one-pot process for the preparation of alkyl 3-cyclopropyl amino-2-[2,4-dibromo-3-(difluoromethoxy) benzoyl]-2-propenoates in which R represents methyl or ethyl, which are valuable intermediates for the production of highly active antibacterial quinolone medicaments.
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