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Conjugates between a peptides and a nucleic acid analog, such as a pna, lna or amorpholino

机译:肽和核酸类似物(如pna,lna或吗啉代)之间的缀合物

摘要

The present invention concerns novel drugs for use in combating infectious micro-organisms, in particular bacteria. More particularly the invention concerns peptide nucleic acid (PNA) sequences, which are modified by conjugating cationic peptides to the PNA in order to obtain novel PNA molecules with enhanced anti-infective properties.
机译:本发明涉及用于抵抗传染性微生物特别是细菌的新型药物。更具体地,本发明涉及肽核酸(PNA)序列,其通过将阳离子肽与PNA缀合而修饰,以获得具有增强的抗感染特性的新型PNA分子。

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