首页> 外国专利> PREPARATION OF A COMPOSITION AGAINST HEPATITIS B-, HI-, PARAMYXO- AND ORTHOMYXOVIRUSES

PREPARATION OF A COMPOSITION AGAINST HEPATITIS B-, HI-, PARAMYXO- AND ORTHOMYXOVIRUSES

机译:制备抗乙型肝炎,高发性疟原虫,正黏性肝炎和正黏性阴道病毒的组合物

摘要

The invention relates to the utilisation of a substance of general formula (I) wherein (A) R1 and R2 are both hydrogen, R3 is halogen, -CF3 is alkoxy with one or two carbon atoms or a halogen substituted alkoxy with one or two carbon atoms and R4 is alkyl with one to four carbon atoms or cycloalkyl with three or four carbon atoms, (B) R1 is hydrogen and R2 and R3 which are the same or different are halogen or -CF3 and R4 is alkyl with one to four carbon atoms or cycloalkyl with three or four carbon atoms, (C) R1 is hydrogen, R2 is alkyl with one or two carbon atoms, R3 is halogen and R4 is alkyl with one to four carbon atoms or cycloalkyl with three or four carbon atoms, (D) R1 is hydrogen, R2 and R3 together are 3',4'-methylendioxy and R4 is alkyl with one to four carbon atoms or cycloalkyl with three or four carbon atoms or the utilisation of a derivative of said formula, whereby said derivative has an open isoxazole ring or a physiologically compatible salt of said formula for producing an agent for the prevention or treatment of virus infections caused by hepatitis B viruses, HI viruses, viruses of the paramyxo group or/and orthomyxo group.
机译:本发明涉及通式(I)的物质的用途,其中(A)R 1和R 2都是氢,R 3是卤素,-CF 3是具有一个或两个碳原子的烷氧基或具有一个或两个碳原子的卤素取代的烷氧基(B)R1是氢,R2和R3相同或不同的是卤素或-CF3,R4是碳数为1-4的烷基(C)R1为氢,R2为具有一个或两个碳原子的烷基,R3为卤素和R4为具有一个或四个碳原子的烷基或具有三个或四个碳原子的环烷基, D)R 1是氢,R 2和R 3一起是3′,4′-甲基二烯氧基,并且R 4是具有1-4个碳原子的烷基或具有3或4个碳原子的环烷基,或者利用所述式的衍生物,其中所述衍生物具有所述式的开放式异恶唑环或生理相容性盐用于生产用作预防或治疗由乙型肝炎病毒,HI病毒,副粘病毒组或/和正粘病毒组病毒引起的病毒感染的药物。

著录项

  • 公开/公告号WO0040242A3

    专利类型

  • 公开/公告日2000-11-16

    原文格式PDF

  • 申请/专利权人 AXXIMA PHARMACEUTICALS AG;ULLRICH AXEL;

    申请/专利号WO1999EP10463

  • 发明设计人 ULLRICH AXEL;

    申请日1999-12-29

  • 分类号A61K31/42;A61P31/12;A61P31/14;A61P31/16;

  • 国家 WO

  • 入库时间 2022-08-22 01:19:26

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