RUFOMYCINS AND DERIVATIVES THEREOF USEFUL AS INHIBITORS OF MULTI-DRUG RESISTANCE ASSOCIATED PROTEIN-1 (MRP-1)

摘要

The present invention provides rufomycin factors and derivatives thereof useful as inhibitors of multi-drug resistant protein. As such these compounds are useful in combination therapy for the treatment of multi-drug resistant diseases. The present invention also provides novel rufomycin factors and derivatives thereof and their pharmaceutical compositions.