1,2,4-TRIAZOLO 1,5-cPYRIMIDINE HETEROCYCLIC ANALOGUES HAVING ANTAGONISTIC ACTIVITY ON ADENOSINE A 2a? RECEPTOR

摘要

The compounds of general formula (I), wherein A is a pyrazole, imidazole or triazole ring, R is formula (II), wherein R1 and R2, which are the same or different, are H, OH, halogen, C1-4 alkoxy, C1-4 alkyl, nitro, amino, cyano, C1-4 haloalkyl, C1-4 haloalkoxy, carboxy, carboxamido groups; moreover the OH group, together with one of R1 or R2, or R1 and R2, can form the methylenedioxy group -O-CH2-O-; n is an integer from 0 to 4, are useful as therapeutical agents.