A NOVEL POLYPEPTIDE, AN EXTERNAL DYNEIN ARMS DHC1ALPHA47 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE

摘要

The present invention discloses a novel polypeptide, an external dynein arms Dhcla1pha47, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as ciliary, villus dyskinesia illness, malignant tumour, hemopathy, developmental disorder, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agoniste against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel external dynein arms Dhcla1pha47.