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Inhibitors of a protease which is capable of cleaving the soluble p55 TNF-receptor from cell-bound TNF-receptor
Inhibitors of a protease which is capable of cleaving the soluble p55 TNF-receptor from cell-bound TNF-receptor
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机译:能够从细胞结合的TNF受体上裂解可溶性p55 TNF受体的蛋白酶抑制剂
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摘要
Molecules which influence the shedding of the cell-bound p55 Tumor Necrosis Factor receptor (p55-TNF-R), are provided, together with methods of producing them. More particularly, the invention relates to proteases which cleave the cell-bound p55 TNF-R thus creating the soluble receptor and to inhibitors to these proteases comprising sequence asn-172 to thr-182 of p55-TNF-R or muteins thereof.
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