Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances

摘要

Prodn. of 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls (I) comprises: (a) reacting 2,2'-dimethyl-1,1'-binaphthyl (II) with a brominating agent in a solvent to form 2,2'-bis(bromomethyl)-1,1'-binaphthyl (III) and other brominated binaphthyls; (b) opt. removing unreacted brominating agent, reacted brominating agent and/or solvent; and (c) reacting the prod. with an alkyl diphenylphosphinite of formula RO-P(Ar)2 (IV) at 70-180 degrees C, opt. in a solvent; where = R = 1-5C alkyl; and Ar = phenyl opt. mono- or disubstd. by 1-4C alkyl, CF3, F, Cl or Br. Also claimed are cpds. of formula (IA): Ar' = phenyl mono- or disubstd. by 1-4C alkyl, CF3, F, Cl or Br. Step (a) comprises reacting (II) with N-bromosuccinimide (NBS) in chlorobenzene and/or dichlorobenzene, either at -10 to +75 (esp. 0-40) degrees C in the presence of light with a wavelength of 10-10,000 nm, or at 25-150 (esp. 40-135) degrees C in the presence of a free radical source. Step (c) is effected at 100-170 (esp. 120-160) degrees C, opt. after replacing the (di)chlorobenzene with xylene and/or mesitylene.