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IMMUNOGENIC COMPOSITIONS COMPRISING PORPHYROMONAS GINGIVALIS PEPTIDES AND METHODS
IMMUNOGENIC COMPOSITIONS COMPRISING PORPHYROMONAS GINGIVALIS PEPTIDES AND METHODS
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机译:包含牙龈卟啉单胞菌肽的免疫原性组合物和方法
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摘要
Provided herein are methods and immunogenic compositions useful for protecting mammals from infection and pathology of P. gingivalis. Specifically, arginine-specific proteases of Porphyromonas gingivalis and peptides derived therefrom offer protection against infection. Immunogenic compositions comprising a 50 kDa arginine-specific protease, the high molecular weight complex or peptides from one of the foregoing proteins are capable of protecting against P. gingivalis infection and/or gingivitis and/or periodontitis caused thereby in mammals, including humans.
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