WATER SOLUBLE FLUORESCENT DYES FREE OF AGGREGATION AND SERUM BINDING AND RELATED PRODUCTS AND METHODS

摘要

The present invention relates to labeling component, fluorescence probe, oligonucleotides, hybridization analysis and use the method for the immunoassays and manufacture of these products product. According to the present invention, detectable label mark component contains to the fluorophore-part on two or more small solubilized axial ligands, [preferably these solvent sensitivities and non-specific binding for reducing or eliminating the above problem.