首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR CONTROLLING TRANSFORMATION OF HETEROGENEOUS FUNGI AND CONTROLLING PROCESS FOR TRANSFORMATION OF HETEROGENEOUS FUNGI USING SAME

PHARMACEUTICAL COMPOSITION FOR CONTROLLING TRANSFORMATION OF HETEROGENEOUS FUNGI AND CONTROLLING PROCESS FOR TRANSFORMATION OF HETEROGENEOUS FUNGI USING SAME

机译:用于控制非均质真菌转化的药物组合物和用于控制非均质真菌转化过程的药物组合物

摘要

PURPOSE: A pharmaceutical composition for controlling transformation of heterogeneous fungi and a controlling process for transformation of heterogeneous fungi using same are provided, which improves infections by heterogeneous fungi effectively. CONSTITUTION: A process for the preparation of pharmaceutical composition for controlling transformation of heterogeneous fungi comprises: preparing culturing extract powder of Candida albicans; adding the dried powder to methanol while stirring, and dissolving for 1-2hrs and filtering to remove non-soluble materials; concentrating under decompression the methanol fraction to get powder; adding the powder to water while stirring, and adding 2times of hexane and fractionizing; concentrating under decompression, and drying to get oily compound; dissolving the compound in 90% acetonitril and separating; processing the secondary high-speed liquid chromatography; concentrating the active fractions, and drying to get oily pure transformed control substances; and analyzing the transformed control substances using spectroscopic method.
机译:用途:提供一种控制异种真菌转化的药物组合物,以及使用该药物组合物控制异种真菌转化的方法,可有效改善异种真菌的感染。组成:控制异质真菌转化的药物组合物的制备方法包括:制备白色念珠菌的培养提取物粉末;在搅拌下将干燥的粉末加入甲醇中,溶解1-2小时,过滤除去不溶物。减压浓缩甲醇馏分,得到粉末。在搅拌下将粉末加入水中,并加入2倍己烷并分馏。减压浓缩,干燥得到油状化合物。将该化合物溶于90%乙腈中并分离;处理二次高速液相色谱;浓缩活性部分,干燥得到油状纯净的转化控制物质。并使用光谱法分析了转化后的对照物质。

著录项

  • 公开/公告号KR20010002012A

    专利类型

  • 公开/公告日2001-01-05

    原文格式PDF

  • 申请/专利权人 CHA IL MOO;OH KI BONG;

    申请/专利号KR19990021575

  • 发明设计人 CHA IL MOO;OH KI BONG;

    申请日1999-06-10

  • 分类号A61K31/01;

  • 国家 KR

  • 入库时间 2022-08-22 01:14:20

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