首页> 外国专利> 2--1--35--3--4--4-3-5--14-124- Polymorphic form of the tachykinin receptor antagonist 2-R-1-R-35-bistrifluoromethylphenylethoxy-3-S-4-fluorophenyl-4-3-5-oxo-1H4H-124-triazolomethylmorpholine

2--1--35--3--4--4-3-5--14-124- Polymorphic form of the tachykinin receptor antagonist 2-R-1-R-35-bistrifluoromethylphenylethoxy-3-S-4-fluorophenyl-4-3-5-oxo-1H4H-124-triazolomethylmorpholine

机译:2--1--35--3--4--4-3-5--14-124-速激肽受体拮抗剂2-R-1-R-35-双三氟甲基苯基乙氧基-3-S-4的多晶型形式-氟苯基-4-3-5-氧代-1H4H-124-三唑并甲基吗啉

摘要

The present invention is the central nervous system diseases, inflammatory diseases, pain or migraine, useful in the treatment or prevention of asthma and vomiting tachykinins receptor antagonist compound 2- (R) - (1- (R) - (3,5- bis a (trifluoromethyl) phenyl) ethoxy) -3- (S) - (4-fluoro) phenyl-4- (3-5 (-oxo -1H, 4H-1,2,4- triazolo) methyl know relates to a novel polymorphic form of the polymorphic morpholine-type pharmaceutical formulation when included in other known forms of 2- (R) -. (1- (R) - (3,5- bis ( trifluoromethyl) phenyl) ethoxy) -3- (S) - (4-fluoro) phenyl-4- (3-5 (-oxo -1H, 4H-1,2,4- triazolo) methylmorpholine morpholin than is advantageous in the thermodynamic stability and suitability surface
机译:本发明是中枢神经系统疾病,炎性疾病,疼痛或偏头痛,可用于治疗或预防哮喘和呕吐速激肽受体拮抗剂化合物2-(R)-(1-(R)-(3,5-bis) (三氟甲基)苯基)乙氧基)-3-(S)-(4-氟)苯基-4-(3-5(-氧代-1H,4H-1,2,4-三唑)甲基)多晶型吗啉型药物制剂的多晶型形式,包括在2-(R)-。(1-(R)-(3,5-双(三氟甲基)苯基)乙氧基)-3-(S)的其他已知形式中-(4-氟)苯基-4-(3-5(-氧代-1H,4H-1,2,4-三唑并)甲基吗啉吗啉比在热力学稳定性和适用性表面上有利

著录项

  • 公开/公告号KR20010020593A

    专利类型

  • 公开/公告日2001-03-15

    原文格式PDF

  • 申请/专利权人 폴락 돈나 엘.;

    申请/专利号KR19997012571

  • 发明设计人 크로커루이스;맥컬리제임스;

    申请日1999-12-30

  • 分类号C07D265/32;

  • 国家 KR

  • 入库时间 2022-08-22 01:14:02

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