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PHARMACEUTICAL COMPOSITION FOR TREATMENT OF LIVER CANCER CONTAINING DIAMINEDITHIOL-RADIOACTIVE RHENIUM COMPLEX AND LIPIODOL, PRODUCTION AND KIT FOR PRODUCTION THEREOF
PHARMACEUTICAL COMPOSITION FOR TREATMENT OF LIVER CANCER CONTAINING DIAMINEDITHIOL-RADIOACTIVE RHENIUM COMPLEX AND LIPIODOL, PRODUCTION AND KIT FOR PRODUCTION THEREOF
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机译:用于治疗含双氨基二巯基-放射性AC配合物和利多多的肝癌的药物组合物,生产及其生产用试剂盒
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摘要
PURPOSE: A composition for the treatment of liver cancer containing diaminedithiol-radioactive and a kit for producing the same are provided. Therefore, the composition exhibits excellent effect on treating liver cancer without side effects when injected to liver cancer patients through the hepatic artery. CONSTITUTION: Diaminedithiol, a reducing agent and an auxiliary agent are reacted with radioactive rhenium to produce a radioactive rhenium complex, which is dissolved in lipiodol to produce the titled composition represented by formula 1, wherein the reducing agent and auxiliary agent are tin chloride and tartaric acid respectively. In formula, R1 to R12 are each independently H or C1-5 lower alkyl.
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