首页> 外国专利> LIPID-A ANALOGS FOR INDUCING THERAPEUTIC ANTIBODY AND HAVING ANTICANCER AND ANTIVIRUS ACTIVITIES: MONOSACCHARIDE AND DISACCHARIDE COMPOUNDS

LIPID-A ANALOGS FOR INDUCING THERAPEUTIC ANTIBODY AND HAVING ANTICANCER AND ANTIVIRUS ACTIVITIES: MONOSACCHARIDE AND DISACCHARIDE COMPOUNDS

机译:诱导治疗性抗体并具有抗癌和抗病毒活性的Lipid-A类似物:单糖和二糖化合物

摘要

PURPOSE: Provided is a compound which induces an antibody binding to lipid-A and immunity to gram-negative bacteria, prevents virus infection, inhibits the growth of cancer cells, and binds to a lipid-A receptor. Also, provided is a composition containing the same. CONSTITUTION: A compound is represented by the formula(1), wherein each of R1, R1', R2, and R2' is a branched or linear, substituted or unsubstituted, C1-12 alkyl, alkene or alkyne group; and R3 is OH, OCH3, CH2COOH or a group represented by the formula.
机译:目的:提供一种化合物,其诱导与脂质A结合的抗体和对革兰氏阴性细菌的免疫力,防止病毒感染,抑制癌细胞的生长,并与脂质A受体结合。另外,提供了包含该组合物的组合物。组成:一种化合物,由式(1)表示,其中R 1,R 1',R 2和R 2'中的每一个是支链或直链,取代或未取代的C 1-12烷基,链烯基或炔基; R 3为OH,OCH 3,CH 2 COOH或下式表示的基团。

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