NUCLEOTIDE SEQUENCE AND AMINO ACID SEQUENCE OF HCV HYPERVARIABLE REGION

摘要

PURPOSE: Provided are a nucleotide sequence of HCV hypervariable region and an amino acid sequence derived therefrom. CONSTITUTION: An HCV polypeptide contains at least one of displaced amino acid in HCV hypervariable region of 384-410 amino acids, represented by TTHTTGGTAARTTSGLTSFSPGPAQK. The polypeptide can be manufactured by the steps of: preparing an expression vector including DNA which contains a nucleotide sequence of HCV polypeptide; transforming a microbe with the vector; and culturing the transformed microbe.