RECOMBINANT ANTIBODY WITH SPECIFICITY TO CD4, METHOD OF ITS PREPARING AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PATIENTS WITH PSORIASIS

摘要

FIELD: genetic engineering of proteins, medicine, pharmacy. SUBSTANCE: invention relates to recombinant antibody containing region of Old World monkey antibody and region of human antibody. Recombinant antibody consists of variable regions of heavy and light chains of immunoglobulin of Old World monkey and human constant regions. Antibody shows specificity to CD4. Recombinant antibody is a component of pharmaceutical composition that can be used for treatment of patients with psoriasis. EFFECT: valuable medicinal properties of recombinant antibody. 6 cl, 28 dwg, 4 ex