A method for determining the lipid - binding constants of substances in aqueous solution of amphiphilic molecules on surfaces

摘要

The invention relates to analysis of the interactions between substances or materials and surfaces or boundary surfaces made up of amphiphilic molecules, whereby distribution coefficients and/or binding constants are determined. To achieve this, the invention uses a support material which is covered with amphiphilic molecules in a so-called liquid phase in such a way that the lateral diffusion of the amphiphilic molecules remains unimpeded. The invention also relates to a kit which is used for the above analyses and to a method for analyzing said interactions in terms of column chromatography, especially high pressure liquid chromatography.