method for the determination of rheumatoid factor and kit

摘要

A fundamental method for assaying a glycoconjugate such as a glycoprotein and a glycolipid, which falls within the category of the sandwich method and which comprises using, as a first reactant, a modified substance which has been suffered from modification at its sugar chain and has been lost its avidity for a sugar-chain-binding substance, and using a substance capable of binding to the sugar chain of a glycoconjugate as a second reactant. In the case of an assay of a rheumatoid factor which is one of glycoconjugates, a modified IgG and a lectin are used as the first reactant and the second reactant, respectively.