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A PROCEDURE FOR THE PREPARATION OF NON-PARTICULAR MACROBIOMOMOMODELS WITH A STRONG NEGATIVE BODY, WHICH ARE CONNECTED TO PLASTICS
A PROCEDURE FOR THE PREPARATION OF NON-PARTICULAR MACROBIOMOMOMODELS WITH A STRONG NEGATIVE BODY, WHICH ARE CONNECTED TO PLASTICS
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机译:与塑料连接的具有强负体的非颗粒微生物模型的制备方法
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摘要
A method for linking strongly negatively charged biological macromolecules like deoxyribonucleic acid (DNA), ribonucleic acid (RNA) and glycosaminoglycans (GAG) to plastic substrates, comprising contacting the macromolecules and the plastics with a non chaotropic solution containing a salt in an amount of at least 20% of its saturation concentration, or having a pH below the pKa of the charged groups of the macromolecules to be linked. Also disclosed are the products of the method, in particular a microtiter plate with plastic wells coated with the negatively charged non-proteinaceous macrobiomolecules.
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