首页> 外国专利> Compositions containing raffinose or stachyose together with a saponin or arginine, have anti-allergic and anti-inflammatory activity, for the treatment of asthma, eczema, arthroses, and the like

Compositions containing raffinose or stachyose together with a saponin or arginine, have anti-allergic and anti-inflammatory activity, for the treatment of asthma, eczema, arthroses, and the like

机译:包含棉子糖或水苏糖以及皂苷或精氨酸的组合物具有抗过敏和抗炎活性,用于治疗哮喘,湿疹,关节炎等

摘要

The use of compositions containing a polysaccharide (I) having 3 - 5 oside units and at least one D-galactose unit linked by an alpha -1-6 bond to a sucrose unit, and a second compound (II) that is positively charged at physiological pH and stimulates pinocytosis or stimulates membrane penetration. The polysaccharide is of formula (I) R1 - R4 = H, 1-10C alkyl that may be unsaturated, 1-10C acid function that may be unsaturated, a sulfate, or a sugar. (I) is preferably raffinose or stachyose, or their derivatives. The second compound (II) is preferably a saponin or arginine. The concentration of (I) in the compositions is preferably 0.01 - 20% by weight, and that of (II) is preferably 5 - 20% of the weight of (I).
机译:包含以下的组合物的用途:包含具有3-5个糖苷单元和至少一个通过α-1-6键与蔗糖单元连接的D-半乳糖单元的多糖(I),以及一种在12位带正电荷的第二化合物(II)生理pH值并刺激胞饮作用或刺激膜渗透。多糖具有式(I),R 1 -R 4 = H,可以是不饱和的1-10C烷基,可以是不饱和的1-10C酸官能团,硫酸盐或糖。 (I)优选为棉子糖或水苏糖或其衍生物。第二化合物(II)优选为皂苷或精氨酸。组合物中(I)的浓度优选为0.01-20重量%,(II)的浓度优选为(I)重量的5-20%。

著录项

  • 公开/公告号FR2802414A1

    专利类型

  • 公开/公告日2001-06-22

    原文格式PDF

  • 申请/专利权人 LABORATOIRES G PHARM;

    申请/专利号FR19990016060

  • 发明设计人 MARTINEZ GERARD;FRANCISCO CHRISTIAN;

    申请日1999-12-20

  • 分类号A61K7/48;A61K7/40;A61K31/702;A61P17/00;A61P37/08;A61P29/00;

  • 国家 FR

  • 入库时间 2022-08-22 01:07:47

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